ROCK1 Induces Endothelial-to-Mesenchymal Transition in Glomeruli to Aggravate Albuminuria in Diabetic Nephropathy

Endothelial-to-mesenchymal transition (EndMT) can cause loss of tight junctions, which in glomeruli are associated with albuminuria. Here we evaluated the role of EndMT in the development of albuminuria in diabetic nephropathy (DN). We demonstrated that EndMT occurs in the glomerular endothelium of...

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Publicado en:Sci Rep
Autores principales: Peng, Hui, Li, Yuanqing, Wang, Cheng, Zhang, Jun, Chen, Yanru, Chen, Wenfang, Cao, Jin, Wang, Yanlin, Hu, Zhaoyong, Lou, Tanqi
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2016
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4740844/
https://ncbi.nlm.nih.gov/pubmed/26842599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep20304
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