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ROCK1 Induces Endothelial-to-Mesenchymal Transition in Glomeruli to Aggravate Albuminuria in Diabetic Nephropathy

Endothelial-to-mesenchymal transition (EndMT) can cause loss of tight junctions, which in glomeruli are associated with albuminuria. Here we evaluated the role of EndMT in the development of albuminuria in diabetic nephropathy (DN). We demonstrated that EndMT occurs in the glomerular endothelium of...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Peng, Hui, Li, Yuanqing, Wang, Cheng, Zhang, Jun, Chen, Yanru, Chen, Wenfang, Cao, Jin, Wang, Yanlin, Hu, Zhaoyong, Lou, Tanqi
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4740844/
https://ncbi.nlm.nih.gov/pubmed/26842599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep20304
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