ROCK1 Induces Endothelial-to-Mesenchymal Transition in Glomeruli to Aggravate Albuminuria in Diabetic Nephropathy

Endothelial-to-mesenchymal transition (EndMT) can cause loss of tight junctions, which in glomeruli are associated with albuminuria. Here we evaluated the role of EndMT in the development of albuminuria in diabetic nephropathy (DN). We demonstrated that EndMT occurs in the glomerular endothelium of...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Peng, Hui, Li, Yuanqing, Wang, Cheng, Zhang, Jun, Chen, Yanru, Chen, Wenfang, Cao, Jin, Wang, Yanlin, Hu, Zhaoyong, Lou, Tanqi
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2016
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4740844/
https://ncbi.nlm.nih.gov/pubmed/26842599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep20304
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