Senescent peritoneal mesothelium induces a pro-angiogenic phenotype in ovarian cancer cells in vitro and in a mouse xenograft model in vivo

It is believed that senescent cells contribute to the progression of primary and metastatic tumors, however, the exact mechanisms of this activity remain elusive. In this report we show that senescent human peritoneal mesothelial cells (HPMCs) alter the secretory profile of ovarian cancer cells (A27...

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Veröffentlicht in:Clin Exp Metastasis
Hauptverfasser: Mikuła-Pietrasik, Justyna, Sosińska, Patrycja, Naumowicz, Eryk, Maksin, Konstantin, Piotrowska, Hanna, Woźniak, Aldona, Szpurek, Dariusz, Książek, Krzysztof
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer Netherlands 2015
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4740564/
https://ncbi.nlm.nih.gov/pubmed/26433963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10585-015-9753-y
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