Senescence-related deterioration of intercellular junctions in the peritoneal mesothelium promotes the transmesothelial invasion of ovarian cancer cells

Mechanisms of transmesothelial invasion of ovarian cancer are still poorly understood. Here we examined whether this phenomenon may be determined by an expression of intercellular junctions in peritoneal mesothelial cells (PMCs). Analysis of ovarian tumors showed that cancer cells are localized belo...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Pakuła, Martyna, Witucka, Anna, Uruski, Paweł, Radziemski, Artur, Moszyński, Rafał, Szpurek, Dariusz, Maksin, Konstantin, Woźniak, Aldona, Sajdak, Stefan, Tykarski, Andrzej, Mikuła-Pietrasik, Justyna, Książek, Krzysztof
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6527686/
https://ncbi.nlm.nih.gov/pubmed/31110245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-44123-4
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