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Senescent peritoneal mesothelium induces a pro-angiogenic phenotype in ovarian cancer cells in vitro and in a mouse xenograft model in vivo

It is believed that senescent cells contribute to the progression of primary and metastatic tumors, however, the exact mechanisms of this activity remain elusive. In this report we show that senescent human peritoneal mesothelial cells (HPMCs) alter the secretory profile of ovarian cancer cells (A27...

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Detalhes bibliográficos
Publicado no:Clin Exp Metastasis
Main Authors: Mikuła-Pietrasik, Justyna, Sosińska, Patrycja, Naumowicz, Eryk, Maksin, Konstantin, Piotrowska, Hanna, Woźniak, Aldona, Szpurek, Dariusz, Książek, Krzysztof
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4740564/
https://ncbi.nlm.nih.gov/pubmed/26433963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10585-015-9753-y
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