Inhibition of Cyclic Adenosine Monophosphate (cAMP)-response Element-binding Protein (CREB)-binding Protein (CBP)/β-Catenin Reduces Liver Fibrosis in Mice

Wnt/β-catenin is involved in every aspect of embryonic development and in the pathogenesis of many human diseases, and is also implicated in organ fibrosis. However, the role of β-catenin-mediated signaling on liver fibrosis remains unclear. To explore this issue, the effects of PRI-724, a selective...

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Vydáno v:EBioMedicine
Hlavní autoři: Osawa, Yosuke, Oboki, Keisuke, Imamura, Jun, Kojika, Ekumi, Hayashi, Yukiko, Hishima, Tsunekazu, Saibara, Toshiji, Shibasaki, Futoshi, Kohara, Michinori, Kimura, Kiminori
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2015
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4740320/
https://ncbi.nlm.nih.gov/pubmed/26870800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2015.10.010
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