Linezolid Trough Concentrations Correlate with Mitochondrial Toxicity-Related Adverse Events in the Treatment of Chronic Extensively Drug-Resistant Tuberculosis

Long-term linezolid use is limited by mitochondrial toxicity-associated adverse events (AEs). Within a prospective, randomized controlled trial of linezolid to treat chronic extensively drug-resistant tuberculosis, we serially monitored the translational competence of mitochondria isolated from peri...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:EBioMedicine
मुख्य लेखकों: Song, Taeksun, Lee, Myungsun, Jeon, Han-Seung, Park, Yumi, Dodd, Lori E., Dartois, Véronique, Follman, Dean, Wang, Jing, Cai, Ying, Goldfeder, Lisa C., Olivier, Kenneth N., Xie, Yingda, Via, Laura E., Cho, Sang Nae, Barry, Clifton E., Chen, Ray Y.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Elsevier 2015
विषय:
Research Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4740314/
https://ncbi.nlm.nih.gov/pubmed/26870788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2015.09.051
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