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Signaling mechanisms of bortezomib in TRAF3-deficient mouse B lymphoma and human multiple myeloma cells

Bortezomib, a clinical drug for multiple myeloma (MM) and mantle cell lymphoma, exhibits complex mechanisms of action, which vary depending on the cancer type and the critical genetic alterations of each cancer. Here we investigated the signaling mechanisms of bortezomib in mouse B lymphoma and huma...

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Detalhes bibliográficos
Publicado no:Leuk Res
Main Authors: Edwards, Shanique K.E., Han, Yeming, Liu, Yingying, Kreider, Benjamin Z., Liu, Yan, Grewal, Sukhdeep, Desai, Anand, Baron, Jacqueline, Moore, Carissa R., Luo, Chang, Xie, Ping
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4740239/
https://ncbi.nlm.nih.gov/pubmed/26740054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.leukres.2015.12.005
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