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Expression and function of a novel isoform of Sox5 in malignant B cells

Using a mouse model with the tumor suppressor TRAF3 deleted from B cells, we identified Sox5 as a gene strikingly up-regulated in B lymphomas. Sox5 proteins were not detected in normal or premalignant TRAF3(-/-)B cells even after treatment with B cell stimuli. The Sox5 expressed in TRAF3(-/-)B lymph...

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Detalhes bibliográficos
Main Authors: Edwards, Shanique K.E., Desai, Anand, Liu, Yan, Moore, Carissa R., Xie, Ping
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3947564/
https://ncbi.nlm.nih.gov/pubmed/24418753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.leukres.2013.12.016
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