Genome-wide association study and targeted metabolomics identifies sex-specific association of CPS1 with coronary artery disease

Metabolites derived from dietary choline and L-carnitine, such as trimethylamine N-oxide and betaine, have recently been identified as novel risk factors for atherosclerosis in mice and humans. We sought to identify genetic factors associated with plasma betaine levels and determine their effect on...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Commun
Prif Awduron: Hartiala, Jaana A., Wilson Tang, W. H., Wang, Zeneng, Crow, Amanda L., Stewart, Alexandre F. R., Roberts, Robert, McPherson, Ruth, Erdmann, Jeanette, Willenborg, Christina, Hazen, Stanley L., Allayee, Hooman
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2016
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4740183/
https://ncbi.nlm.nih.gov/pubmed/26822151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10558
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