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Genome-wide association study and targeted metabolomics identifies sex-specific association of CPS1 with coronary artery disease

Metabolites derived from dietary choline and L-carnitine, such as trimethylamine N-oxide and betaine, have recently been identified as novel risk factors for atherosclerosis in mice and humans. We sought to identify genetic factors associated with plasma betaine levels and determine their effect on...

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Publicado no:Nat Commun
Main Authors: Hartiala, Jaana A., Wilson Tang, W. H., Wang, Zeneng, Crow, Amanda L., Stewart, Alexandre F. R., Roberts, Robert, McPherson, Ruth, Erdmann, Jeanette, Willenborg, Christina, Hazen, Stanley L., Allayee, Hooman
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4740183/
https://ncbi.nlm.nih.gov/pubmed/26822151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10558
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