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Analysis of Signaling Endosome Composition and Dynamics Using SILAC in Embryonic Stem Cell-Derived Neurons

Neurons require efficient transport mechanisms such as fast axonal transport to ensure neuronal homeostasis and survival. Neurotrophins and their receptors are conveyed via fast axonal retrograde transport of signaling endosomes to the soma, where they elicit transcriptional responses. Despite the e...

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Bibliographische Detailangaben
Veröffentlicht in:Mol Cell Proteomics
Hauptverfasser: Debaisieux, Solène, Encheva, Vesela, Chakravarty, Probir, Snijders, Ambrosius P., Schiavo, Giampietro
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Biochemistry and Molecular Biology 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4739672/
https://ncbi.nlm.nih.gov/pubmed/26685126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M115.051649
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