Rare Cell Proteomic Reactor Applied to Stable Isotope Labeling by Amino Acids in Cell Culture (SILAC)-based Quantitative Proteomics Study of Human Embryonic Stem Cell Differentiation

The molecular basis governing the differentiation of human embryonic stem cells (hESCs) remains largely unknown. Systems-level analysis by proteomics provides a unique approach to tackle this question. However, the requirement of a large number of cells for proteomics analysis (i.e. 10(6)–10(7) cell...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Tian, Ruijun, Wang, Shuai, Elisma, Fred, Li, Li, Zhou, Hu, Wang, Lisheng, Figeys, Daniel
التنسيق: Artigo
اللغة:Inglês
منشور في: The American Society for Biochemistry and Molecular Biology 2011
الموضوعات:
Special Issue
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC3033666/
https://ncbi.nlm.nih.gov/pubmed/20530636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M110.000679
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