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Regulation of Nuclear Receptor Nur77 by miR-124

The nuclear receptor Nur77 is commonly upregulated in adult cancers and has oncogenic functions. Nur77 is an immediate-early response gene that acts as a transcription factor to promote proliferation and protect cells from apoptosis. Conversely, Nur77 can translocate to the mitochondria and induce a...

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Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Tenga, Alexa, Beard, Jordan A., Takwi, Apana, Wang, Yue-Ming, Chen, Taosheng
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4739595/
https://ncbi.nlm.nih.gov/pubmed/26840408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0148433
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