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miR-137 regulates the constitutive androstane receptor and modulates doxorubicin sensitivity in parental and doxorubicin-resistant neuroblastoma cells

Chemotherapy is the most common treatment for cancer. However, multidrug resistance (MDR) remains a major obstacle to effective chemotherapy, limiting the efficacy of both conventional chemotherapeutic and novel biologic agents. The constitutive androstane receptor (CAR), a xenosensor, is a key regu...

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Detalhes bibliográficos
Main Authors: Takwi, Apana A, Wang, Yue-Ming, Wu, Jing, Michaelis, Martin, Cinatl, Jindrich, Chen, Taosheng
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3922897/
https://ncbi.nlm.nih.gov/pubmed/23934188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2013.330
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