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The Role of T Cell Costimulation via DNAM-1 in Kidney Transplantation

DNAX accessory protein-1 (DNAM-1, CD226) is a co-stimulatory and adhesion molecule expressed mainly by natural killer cells and T cells. DNAM-1 and its two ligands CD112 and CD155 are important in graft-versus-host disease, but their role in solid organ transplantation is largely unknown. We investi...

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Veröffentlicht in:PLoS One
Hauptverfasser: Kraus, Anna K., Chen, Jin, Edenhofer, Ilka, Ravens, Inga, Gaspert, Ariana, Cippà, Pietro E., Mueller, Steffen, Wuthrich, Rudolf P., Segerer, Stephan, Bernhardt, Guenter, Fehr, Thomas
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4739582/
https://ncbi.nlm.nih.gov/pubmed/26840537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0147951
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