In vivo activation of transferred regulatory T cells specific for third‐party exogenous antigen controls GVH disease in mice

Treg cells hold enormous promise for therapeutic application in GVH disease, a lethal complication of allogeneic HSC transplantation. Mouse studies showed that donor‐derived recipient‐specific Treg (rsTreg) cells are far more efficient than polyclonal Treg cells in suppressing GVH disease. However,...

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Vydáno v:Eur J Immunol
Hlavní autoři: Martin, Gaëlle H., Grégoire, Sylvie, Landau, Dan A., Pilon, Caroline, Grinberg‐Bleyer, Yenkel, Charlotte, Frédéric, Mège, Jean‐Pierre, Chatenoud, Lucienne, Salomon, Benoît L., Cohen, José L.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4738555/
https://ncbi.nlm.nih.gov/pubmed/23765389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201343449
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