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In vivo activation of transferred regulatory T cells specific for third‐party exogenous antigen controls GVH disease in mice
Treg cells hold enormous promise for therapeutic application in GVH disease, a lethal complication of allogeneic HSC transplantation. Mouse studies showed that donor‐derived recipient‐specific Treg (rsTreg) cells are far more efficient than polyclonal Treg cells in suppressing GVH disease. However,...
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| Pubblicato in: | Eur J Immunol |
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| Autori principali: | , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
John Wiley and Sons Inc.
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4738555/ https://ncbi.nlm.nih.gov/pubmed/23765389 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201343449 |
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