Tissue-restricted control of established central nervous system autoimmunity by TNF receptor 2–expressing Treg cells

CD4(+)Foxp3(+) regulatory T (Treg) cells are central modulators of autoimmune diseases. However, the timing and location of Treg cell–mediated suppression of tissue-specific autoimmunity remain undefined. Here, we addressed these questions by investigating the role of tumor necrosis factor (TNF) rec...

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Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Ronin, Emilie, Pouchy, Charlotte, Khosravi, Maryam, Hilaire, Morgane, Grégoire, Sylvie, Casrouge, Armanda, Kassem, Sahar, Sleurs, David, Martin, Gaëlle H., Chanson, Noémie, Lombardi, Yannis, Lalle, Guilhem, Wajant, Harald, Auffray, Cédric, Lucas, Bruno, Marodon, Gilles, Grinberg-Bleyer, Yenkel, Salomon, Benoît L.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2021
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8020675/
https://ncbi.nlm.nih.gov/pubmed/33766913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2014043118
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