UHRF1 regulation of the Keap1–Nrf2 pathway in pancreatic cancer contributes to oncogenesis

The cellular defence protein Nrf2 is a mediator of oncogenesis in pancreatic ductal adenocarcinoma (PDAC) and other cancers. However, the control of Nrf2 expression and activity in cancer is not fully understood. We previously reported the absence of Keap1, a pivotal regulator of Nrf2, in ∼70% of PD...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:J Pathol
Main Authors: Abu‐Alainin, Wafa, Gana, Thompson, Liloglou, Triantafillos, Olayanju, Adedamola, Barrera, Lawrence N, Ferguson, Robert, Campbell, Fiona, Andrews, Timothy, Goldring, Christopher, Kitteringham, Neil, Park, Brian K, Nedjadi, Taoufik, Schmid, Michael C, Slupsky, Joseph R, Greenhalf, William, Neoptolemos, John P, Costello, Eithne
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley & Sons, Ltd 2015
Fag:
Original Papers
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4738372/
https://ncbi.nlm.nih.gov/pubmed/26497117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.4665
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker