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S100A8 and S100A9 proteins form part of a paracrine feedback loop between pancreatic cancer cells and monocytes

BACKGROUND: The secretion of soluble factors enables communication between tumour cells and the surrounding microenvironment and plays an important role in oncogenesis. Pancreatic ductal adenocarcinoma (PDAC) is characterised by a highly reactive microenvironment, harbouring a variety of cell types,...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Nedjadi, Taoufik, Evans, Anthony, Sheikh, Adnan, Barerra, Lawrence, Al-Ghamdi, Suliman, Oldfield, Lucy, Greenhalf, W., Neoptolemos, John P., Costello, Eithne
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6296088/
https://ncbi.nlm.nih.gov/pubmed/30558665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-018-5161-4
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