F-actin-rich contractile endothelial pores prevent vascular leakage during leukocyte diapedesis through local RhoA signalling

During immune surveillance and inflammation, leukocytes exit the vasculature through transient openings in the endothelium without causing plasma leakage. However, the exact mechanisms behind this intriguing phenomenon are still unknown. Here we report that maintenance of endothelial barrier integri...

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Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Nat Commun
Κύριοι συγγραφείς: Heemskerk, Niels, Schimmel, Lilian, Oort, Chantal, van Rijssel, Jos, Yin, Taofei, Ma, Bin, van Unen, Jakobus, Pitter, Bettina, Huveneers, Stephan, Goedhart, Joachim, Wu, Yi, Montanez, Eloi, Woodfin, Abigail, van Buul, Jaap D.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Nature Publishing Group 2016
Θέματα:
Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4737874/
https://ncbi.nlm.nih.gov/pubmed/26814335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10493
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