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Aβ-Induced Synaptic Alterations Require the E3 Ubiquitin Ligase Nedd4-1

Alzheimer's disease (AD) is a neurodegenerative disease in which patients experience progressive cognitive decline. A wealth of evidence suggests that this cognitive impairment results from synaptic dysfunction in affected brain regions caused by cleavage of amyloid precursor protein into the p...

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Detalles Bibliográficos
Publicado en:J Neurosci
Main Authors: Rodrigues, Elizabeth M., Scudder, Samantha L., Goo, Marisa S., Patrick, Gentry N.
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4737771/
https://ncbi.nlm.nih.gov/pubmed/26843640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2964-15.2016
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