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Aβ-Induced Synaptic Alterations Require the E3 Ubiquitin Ligase Nedd4-1

Alzheimer's disease (AD) is a neurodegenerative disease in which patients experience progressive cognitive decline. A wealth of evidence suggests that this cognitive impairment results from synaptic dysfunction in affected brain regions caused by cleavage of amyloid precursor protein into the p...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Neurosci
Hauptverfasser: Rodrigues, Elizabeth M., Scudder, Samantha L., Goo, Marisa S., Patrick, Gentry N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4737771/
https://ncbi.nlm.nih.gov/pubmed/26843640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2964-15.2016
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