Cyclosporine A Suppressed Glucose Oxidase Induced P53 Mitochondrial Translocation and Hepatic Cell Apoptosis through Blocking Mitochondrial Permeability Transition

P53 is known as a transcription factor to control apoptotic cell death through regulating a series of target genes in nucleus. There is accumulating evidences show that p53 can directly induce cell apoptosis through transcription independent way at mitochondria. However, the mechanism by which p53 t...

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Bibliographic Details
Published in:Int J Biol Sci
Main Authors: Yu, Weihua, Zhang, Xiaodi, Liu, Jiangzheng, Wang, Xin, Li, Shuang, Liu, Rui, Liao, Nai, Zhang, Tao, Hai, Chunxu
Format: Artigo
Language:Inglês
Published: Ivyspring International Publisher 2016
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4737676/
https://ncbi.nlm.nih.gov/pubmed/26884717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.13716
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