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Selective and Potent Proteomimetic Inhibitors of Intracellular Protein–Protein Interactions
Inhibition of protein–protein interactions (PPIs) represents a major challenge in chemical biology and drug discovery. α‐Helix mediated PPIs may be amenable to modulation using generic chemotypes, termed “proteomimetics”, which can be assembled in a modular manner to reproduce the vectoral presentat...
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| Pubblicato in: | Angew Chem Weinheim Bergstr Ger |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
WILEY‐VCH Verlag
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4737265/ https://ncbi.nlm.nih.gov/pubmed/26877561 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ange.201410810 |
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