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Selective and Potent Proteomimetic Inhibitors of Intracellular Protein–Protein Interactions**
Inhibition of protein–protein interactions (PPIs) represents a major challenge in chemical biology and drug discovery. α-Helix mediated PPIs may be amenable to modulation using generic chemotypes, termed “proteomimetics”, which can be assembled in a modular manner to reproduce the vectoral presentat...
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| Publicado no: | Angew Chem Int Ed Engl |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
WILEY-VCH Verlag
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4506525/ https://ncbi.nlm.nih.gov/pubmed/25651514 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201410810 |
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