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Sizing femtogram amounts of dsDNA by single-molecule counting

Modern molecular-biology applications raise renewed interest in sizing minute-amounts of DNA. In this work we utilize single-molecule imaging with in situ size calibration to accurately analyze the size and mass distribution of DNA samples. We exploit the correlation between DNA length and its fluor...

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Pubblicato in:Nucleic Acids Res
Autori principali: Torchinsky, Dmitry, Ebenstein, Yuval
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4737178/
https://ncbi.nlm.nih.gov/pubmed/26365235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv904
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