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Probing binding hot spots at protein–RNA recognition sites

We use evolutionary conservation derived from structure alignment of polypeptide sequences along with structural and physicochemical attributes of protein–RNA interfaces to probe the binding hot spots at protein–RNA recognition sites. We find that the degree of conservation varies across the RNA bin...

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Détails bibliographiques
Publié dans:Nucleic Acids Res
Auteurs principaux: Barik, Amita, Nithin, Chandran, Karampudi, Naga Bhushana Rao, Mukherjee, Sunandan, Bahadur, Ranjit Prasad
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4737170/
https://ncbi.nlm.nih.gov/pubmed/26365245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv876
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