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Probing binding hot spots at protein–RNA recognition sites

We use evolutionary conservation derived from structure alignment of polypeptide sequences along with structural and physicochemical attributes of protein–RNA interfaces to probe the binding hot spots at protein–RNA recognition sites. We find that the degree of conservation varies across the RNA bin...

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Bibliografische gegevens
Gepubliceerd in:Nucleic Acids Res
Hoofdauteurs: Barik, Amita, Nithin, Chandran, Karampudi, Naga Bhushana Rao, Mukherjee, Sunandan, Bahadur, Ranjit Prasad
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4737170/
https://ncbi.nlm.nih.gov/pubmed/26365245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv876
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