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Probing binding hot spots at protein–RNA recognition sites

We use evolutionary conservation derived from structure alignment of polypeptide sequences along with structural and physicochemical attributes of protein–RNA interfaces to probe the binding hot spots at protein–RNA recognition sites. We find that the degree of conservation varies across the RNA bin...

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Библиографические подробности
Опубликовано в: :Nucleic Acids Res
Главные авторы: Barik, Amita, Nithin, Chandran, Karampudi, Naga Bhushana Rao, Mukherjee, Sunandan, Bahadur, Ranjit Prasad
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2016
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4737170/
https://ncbi.nlm.nih.gov/pubmed/26365245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv876
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