Fyn Mediates High Glucose-Induced Actin Cytoskeleton Reorganization of Podocytes via Promoting ROCK Activation In Vitro

Fyn, a member of the Src family of tyrosine kinases, is a key regulator in cytoskeletal remodeling in a variety of cell types. Recent studies have demonstrated that Fyn is responsible for nephrin tyrosine phosphorylation, which will result in polymerization of actin filaments and podocyte damage. Th...

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Udgivet i:J Diabetes Res
Main Authors: Lv, Zhimei, Hu, Mengsi, Ren, Xiaoxu, Fan, Minghua, Zhen, Junhui, Chen, Liqun, Lin, Jiangong, Ding, Nannan, Wang, Qun, Wang, Rong
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi Publishing Corporation 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4736797/
https://ncbi.nlm.nih.gov/pubmed/26881253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/5671803
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