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Loss of Functional Alpha-Synuclein: A Toxic Event in Parkinson’s Disease?

The discovery that alpha-synuclein (α-syn) is the primary component of the neuropathological hallmarks of Parkinson’s disease (PD) and the identification of α-syn mutations in numerous inherited forms of PD has positioned α-syn at the top of the list of important factors in the pathogenesis of PD. B...

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Detalhes bibliográficos
Publicado no:J Parkinsons Dis
Main Authors: Kanaan, Nicholas M., Manfredsson, Fredric P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4736738/
https://ncbi.nlm.nih.gov/pubmed/23938255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JPD-012138
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