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Palladium‐Catalyzed Directed C(sp(3))–H Arylation of Saturated Heterocycles at C‐3 Using a Concise Optimization Approach

Saturated heterocycles, such as THFs, pyrrolidines, piperidines and THPs, are essential components of many biologically active compounds. Examples of C–H functionalization on these important ring systems remain scarce, especially at unactivated positions. Here we report the development of conditions...

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Detalhes bibliográficos
Publicado no:European J Org Chem
Main Authors: Affron, Dominic P., Bull, James A.
Formato: Artigo
Idioma:Inglês
Publicado em: WILEY‐VCH Verlag 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4736452/
https://ncbi.nlm.nih.gov/pubmed/26877706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ejoc.201501300
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