RGS10 deficiency ameliorates the severity of disease in experimental autoimmune encephalomyelitis

BACKGROUND: Regulator of G-protein signaling (RGS) family proteins, which are GTPase accelerating proteins (GAPs) that negatively regulate G-protein-coupled receptors (GPCRs), are known to be important modulators of immune cell activation and function. Various single-nucleotide polymorphisms in RGS...

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Veröffentlicht in:J Neuroinflammation
Hauptverfasser: Lee, Jae-Kyung, Kannarkat, George T., Chung, Jaegwon, Joon Lee, Hyun, Graham, Kareem L., Tansey, Malú G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2016
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4736282/
https://ncbi.nlm.nih.gov/pubmed/26831924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-016-0491-0
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