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Age-related changes in Regulator of G-protein Signaling (RGS)-10 expression in peripheral and central immune cells may influence risk for age-related degeneration

Inflammation in the aging brain increases risk for neurodegenerative disease. In humans, the Regulator of G-protein Signaling (RGS) 10 locus has been associated with age-related maculopathy. Chronic peripheral administration of lipopolysaccharide in the RGS10-null mice induces nigral dopaminergic (D...

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Detalhes bibliográficos
Publicado no:Neurobiol Aging
Main Authors: Kannarkat, George T., Lee, Jae-Kyung, Ramsey, Chenere P., Chung, Jaegwon, Chang, Jianjun, Porter, Isadora, Oliver, Danielle, Shepherd, Kennie, Tansey, Malú G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4417042/
https://ncbi.nlm.nih.gov/pubmed/25784210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2015.02.006
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