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Regulator of G-Protein Signaling-10 Negatively Regulates NF-κB in Microglia and Neuroprotects Dopaminergic Neurons in Hemiparkinsonian Rats

Microglia are the brain-resident macrophages responsible for immune surveillance that become activated in response to injury, infection, environmental toxins, and other stimuli that threaten neuronal survival. Previous work from our group demonstrated that mice deficient in Regulator of G-protein Si...

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Bibliografski detalji
Glavni autori: Lee, Jae-Kyung, Chung, Jaegwon, McAlpine, Fiona E., Tansey, Malú G.
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3326398/
https://ncbi.nlm.nih.gov/pubmed/21849548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1002-11.2011
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