RNF11 modulates microglia activation through NF-κB signalling cascade

Microglia are resident macrophages in the central nervous system (CNS) that play a major role in neuroinflammation and pathogenesis of several neurodegenerative diseases. Upon activation, microglia releases a multitude of pro-inflammatory factors that initiate and sustain an inflammatory response by...

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Hauptverfasser: Dalal, Nirjari V., Pranski, Elaine L., Tansey, Malu G., Lah, James J., Levey, Allan I., Betarbet, Ranjita S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3478679/
https://ncbi.nlm.nih.gov/pubmed/22975135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2012.08.060
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