RING finger protein 11 (RNF11) modulates susceptibility to 6-OHDA-induced nigral degeneration and behavioral deficits through NF-κB signaling in dopaminergic cells

Chronic activation of the NF-κB pathway is associated with progressive neurodegeneration in Parkinson’s disease (PD). Given the role of neuronal RING finger protein 11 (RNF11) as a negative regulator of the NF-κB pathway, in this report we investigated the function of RNF11 in dopaminergic cells in...

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Hauptverfasser: Pranski, Elaine L., Dalal, Nirjari V., Van Sanford, Carson, Herskowitz, Jeremy H., Gearing, Marla, Lazo, Carlos, Miller, Gary W., Lah, James J., Levey, Allan I., Betarbet, Ranjita S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3628953/
https://ncbi.nlm.nih.gov/pubmed/23318928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2012.12.018
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