Suppression of LPS-induced tau hyperphosphorylation by serum amyloid A

BACKGROUND: Accumulation of hyperphosphorylated tau is a major neuropathological feature of tauopathies including Alzheimer’s disease (AD). Serum amyloid A (SAA), an acute-phase protein with cytokine-like property, has been implicated in amyloid deposition. It remains unclear whether SAA affects tau...

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Bibliographic Details
Published in:J Neuroinflammation
Main Authors: Liu, Jin, Wang, Ding, Li, Shu-Qin, Yu, Yang, Ye, Richard D.
Format: Artigo
Language:Inglês
Published: BioMed Central 2016
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4736117/
https://ncbi.nlm.nih.gov/pubmed/26838764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-016-0493-y
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