Actin filament turnover drives leading edge growth during myelin sheath formation in the central nervous system

During central nervous system development, oligodendrocytes wrap their plasma membrane around axons to generate multi-lamellar myelin sheaths. To drive growth at the leading edge of myelin at the interface with the axon, mechanical forces are necessary, but the underlying mechanisms are not known. U...

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Detalhes bibliográficos
Publicado no:Dev Cell
Main Authors: Nawaz, Schanila, Sánchez, Paula, Schmitt, Sebastian, Snaidero, Nicolas, Mitkovski, Mišo, Velte, Caroline, Brückner, Bastian R., Alexopoulos, Ioannis, Czopka, Tim, Jung, Sang Y., Rhee, Jeong S., Janshoff, Andreas, Witke, Walter, Schaap, Iwan A.T., Lyons, David A., Simons, Mikael
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4736019/
https://ncbi.nlm.nih.gov/pubmed/26166299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2015.05.013
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