Actin filament turnover drives leading edge growth during myelin sheath formation in the central nervous system

During central nervous system development, oligodendrocytes wrap their plasma membrane around axons to generate multi-lamellar myelin sheaths. To drive growth at the leading edge of myelin at the interface with the axon, mechanical forces are necessary, but the underlying mechanisms are not known. U...

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Veröffentlicht in:Dev Cell
Hauptverfasser: Nawaz, Schanila, Sánchez, Paula, Schmitt, Sebastian, Snaidero, Nicolas, Mitkovski, Mišo, Velte, Caroline, Brückner, Bastian R., Alexopoulos, Ioannis, Czopka, Tim, Jung, Sang Y., Rhee, Jeong S., Janshoff, Andreas, Witke, Walter, Schaap, Iwan A.T., Lyons, David A., Simons, Mikael
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4736019/
https://ncbi.nlm.nih.gov/pubmed/26166299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2015.05.013
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