Myelin Membrane Assembly Is Driven by a Phase Transition of Myelin Basic Proteins Into a Cohesive Protein Meshwork

Rapid conduction of nerve impulses requires coating of axons by myelin. To function as an electrical insulator, myelin is generated as a tightly packed, lipid-rich multilayered membrane sheath. Knowledge about the mechanisms that govern myelin membrane biogenesis is required to understand myelin dis...

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Main Authors: Aggarwal, Shweta, Snaidero, Nicolas, Pähler, Gesa, Frey, Steffen, Sánchez, Paula, Zweckstetter, Markus, Janshoff, Andreas, Schneider, Anja, Weil, Marie-Theres, Schaap, Iwan A. T., Görlich, Dirk, Simons, Mikael
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3676292/
https://ncbi.nlm.nih.gov/pubmed/23762018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001577
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