Reversal of axonal growth defects in an extraocular fibrosis model by engineering the kinesin–microtubule interface

Mutations in human β3-tubulin (TUBB3) cause an ocular motility disorder termed congenital fibrosis of the extraocular muscles type 3 (CFEOM3). In CFEOM3, the oculomotor nervous system develops abnormally due to impaired axon guidance and maintenance; however, the underlying mechanism linking TUBB3 m...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nat Commun
Egile Nagusiak: Minoura, Itsushi, Takazaki, Hiroko, Ayukawa, Rie, Saruta, Chihiro, Hachikubo, You, Uchimura, Seiichi, Hida, Tomonobu, Kamiguchi, Hiroyuki, Shimogori, Tomomi, Muto, Etsuko
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2016
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4735607/
https://ncbi.nlm.nih.gov/pubmed/26775887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10058
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak