GTP-dependent formation of straight tubulin oligomers leads to microtubule nucleation

Nucleation of microtubules (MTs) is essential for cellular activities, but its mechanism is unknown because of the difficulty involved in capturing rare stochastic events in the early stage of polymerization. Here, combining rapid flush negative stain electron microscopy (EM) and kinetic analysis, w...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Cell Biol
Egile Nagusiak: Ayukawa, Rie, Iwata, Seigo, Imai, Hiroshi, Kamimura, Shinji, Hayashi, Masahito, Ngo, Kien Xuan, Minoura, Itsushi, Uchimura, Seiichi, Makino, Tsukasa, Shirouzu, Mikako, Shigematsu, Hideki, Sekimoto, Ken, Gigant, Benoît, Muto, Etsuko
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Rockefeller University Press 2021
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7871348/
https://ncbi.nlm.nih.gov/pubmed/33544140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.202007033
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