Crystal structure of the N-myristoylated lipopeptide-bound MHC class I complex

The covalent conjugation of a 14-carbon saturated fatty acid (myristic acid) to the amino-terminal glycine residue is critical for some viral proteins to function. This protein lipidation modification, termed N-myristoylation, is targeted by host cytotoxic T lymphocytes (CTLs) that specifically reco...

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Publicado no:Nat Commun
Main Authors: Morita, Daisuke, Yamamoto, Yukie, Mizutani, Tatsuaki, Ishikawa, Takeshi, Suzuki, Juri, Igarashi, Tatsuhiko, Mori, Naoki, Shiina, Takashi, Inoko, Hidetoshi, Fujita, Hiroaki, Iwai, Kazuhiro, Tanaka, Yoshimasa, Mikami, Bunzo, Sugita, Masahiko
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4735555/
https://ncbi.nlm.nih.gov/pubmed/26758274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10356
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