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Major T Cell Response to a Mycolyl Glycolipid Is Mediated by CD1c Molecules in Rhesus Macaques

Human CD1b molecules contain a maze of hydrophobic pockets and a tunnel capable of accommodating the unusually long, branched acyl chain of mycolic acids, an essential fatty acid component of the cell wall of mycobacteria. It has been accepted that CD1b-bound mycolic acids constitute a scaffold for...

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Detalhes bibliográficos
Main Authors: Morita, Daisuke, Hattori, Yuki, Nakamura, Takashi, Igarashi, Tatsuhiko, Harashima, Hideyoshi, Sugita, Masahiko
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3536160/
https://ncbi.nlm.nih.gov/pubmed/23132493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00871-12
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