Molecular Requirements for T Cell Recognition of N-Myristoylated Peptides Derived from the Simian Immunodeficiency Virus Nef Protein

We have recently isolated a rhesus macaque cytotoxic T cell line, 2N5.1, that specifically recognizes an N-myristoylated 5-mer peptide (C(14)-Gly-Gly-Ala-Ile-Ser [C14nef5]) derived from the simian immunodeficiency virus (SIV) Nef protein. Such C14nef5-specific T cells expand in the circulation of SI...

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Detalhes bibliográficos
Main Authors: Morita, Daisuke, Yamamoto, Yukie, Suzuki, Juri, Mori, Naoki, Igarashi, Tatsuhiko, Sugita, Masahiko
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3536395/
https://ncbi.nlm.nih.gov/pubmed/23097434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02142-12
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