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Targeting Prefrontal Cortical Systems for Drug Development: Potential Therapies for Cognitive Disorders

Medications to treat cognitive disorders are increasingly needed, yet researchers have had few successes in this challenging arena. Cognitive abilities in primates arise from highly evolved N-methyl-d-aspartate (NMDA) receptor circuits in layer III of the dorsolateral prefrontal cortex. These circui...

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Bibliografische gegevens
Gepubliceerd in:Annu Rev Pharmacol Toxicol
Hoofdauteurs: Arnsten, Amy F.T., Wang, Min
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4734124/
https://ncbi.nlm.nih.gov/pubmed/26738476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-pharmtox-010715-103617
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