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Guanfacine’s mechanism of action in treating prefrontal cortical disorders: Successful translation across species
The selective norepinephrine (NE) α2A-adrenoceptor (α2A-AR) agonist, guanfacine (Intuniv™), is FDA-approved for treating Attention Deficit Hyperactivity Disorder (ADHD) based on research in animals, a translational success story. Guanfacine is also widely used off-label in additional mental disorder...
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| 發表在: | Neurobiol Learn Mem |
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| 主要作者: | |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
The Author(s). Published by Elsevier Inc.
2020
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7567669/ https://ncbi.nlm.nih.gov/pubmed/33075480 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nlm.2020.107327 |
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